Low dose aspirin risks overwhelm benefits in healthy elderly

'Aspirin-a-day risky in old age' - major study

'Aspirin-a-day risky in old age' - major study

We also found daily low-dose aspirin does not prevent heart attack or stroke when taken by elderly people who hadn't experienced either condition before.

"These findings will help inform prescribing doctors who have always been uncertain about whether to recommend aspirin to healthy patients who do not have a clear medical reason for doing so", John McNeil, head of the Department of Epidemiology and Preventive Medicine at Monash University in Australia, said in a statement.

But the new worldwide study followed 19,114 seniors for an average of 4.7 years.

It found that for older people with no history of heart attack, stroke or congestive heart failure taking a daily aspirin might do more harm than good.

They also attributed the higher mortality in this test group to cancer-related deaths.

The participants took a daily low-dose of aspirin every day for almost five years, with researchers monitoring their health and any occurrences of disease, disability or death.

At the end of the trial, 90.3 percent of the aspirin-treated patients were still alive, compared to 90.5 percent of those who received placebos. The trial will result in a rethinking of global guidelines relating to the use of aspirin to prevent common conditions associated with ageing, he says.

Experts last night urged people to take medical advice from their before deciding whether or not to use aspirin regularly.

Experts disagree on whether Dallas officer could be credible
Secondly, there is no indication that a similar warrant was issued for Guyger since she lived in the apartment below Jean . He described Jean's death as an avoidable tragedy and said the group wants to know why Guyger has not been fired.

'This study shows why it is so important to conduct this type of research, so that we can gain a fuller picture of aspirin's benefits and risks among healthy older persons'. They noted however the escalated rate of bleeding in the team that accrued aspirin, as compared to the team that accrued a placebo.

The clinical trial did not include people who take aspirin for medical reasons as advised by their doctor, including those who have already suffered a heart attack or stroke.

The results of the Aspirin in Reducing Events in the Elderly (ASPREE) trial have been published in three papers in the New England Journal of Medicine. The authors said that "these findings should be interpreted with caution" until more studies are completed, particularly because other research has concluded that the drug helps reduce the risk of colorectal cancer.

"ASPREE is a study that was probably long overdue", he said.

In fact, daily aspirin use increased the risk of death in healthy adults, mostly from cancer.

No individual component of the primary endpoint made a case for the benefit of aspirin, which failed to reduce the risk of cardiovascular disease as well (10.7 versus 11.3 events per 1,000 person-years, HR 0.95, 95% CI 0.83-1.08). At the same time, the rate of hemorrhage was 8.6 events per 1,000 person-years in the aspirin group and 6.2 events in the control group.

So what should older healthy adults do with this new information about aspirin? "In India, self treatment with aspirin is often seen, and it should be strictly forbidden", said Anoop Misra, chairman, Fortis-C-DOC Centre of Excellence for Diabetes, Metabolic Diseases and Endocrinology.

Recommended News

  • Game of Thrones, Mrs. Maisel triumph at Emmys

    Game of Thrones, Mrs. Maisel triumph at Emmys

    Saturday Night Live won, as expected, for variety sketch series, taking its lifetime Emmy total to a record-setting 72 wins. SURPRISE: Alex Borstein won supporting comedy actress for her work on " The Marvelous Mrs.
    Tension mounts over 11-year-old Gaza boy’s killing at border rally

    Tension mounts over 11-year-old Gaza boy’s killing at border rally

    Palestinian president Mahmoud Abbas pictured at a meeting of the Palestine Liberation Organization Executive Committee. Mohammed, a 12 year-old friend also from Jabalia refugee camp, said he was with Abdel Aal when he was hit.
    Watches Issued As Isaac Closes in on Lesser Antilles

    Watches Issued As Isaac Closes in on Lesser Antilles

    Britain is bracing itself for strong winds and heavy rain as Hurricane Helene makes its way across the Atlantic. Hurricane Florence is now generating waves up to 83 feet, almost double the height measured on Tuesday.
  • Samsung investigates alleged Galaxy Note9 fire incident

    Samsung investigates alleged Galaxy Note9 fire incident

    He said that the engineers at Samsung are confident of its safety, and that users do not have to worry about batteries any more. Chung is now filing a lawsuit against Samsung that along with damages is seeking to ban any further sales of the Note 9.
    Meghan Markle mocked by half-sister Samantha in latest rant

    Meghan Markle mocked by half-sister Samantha in latest rant

    If you suddenly bump into her in the corridor, don't panic. "It's this shutdown mechanism she has. What came to light after Trevor and I spoke ended my friendship with Meghan.
    Hurricane Florence: Woman, baby die after tree falls on house

    Hurricane Florence: Woman, baby die after tree falls on house

    A man who was trapped inside his New Bern, North Carolina, home by Tropical Storm Florence spoke with Fox & Friends on Saturday. More than 100 people were rescued and up to 75 more were awaiting rescue on Saturday morning, according to a town official.
  • Russian accused spy's link to Kremlin

    Russian accused spy's link to Kremlin

    The interview with Alexander Petrov and Ruslan Boshirov, named as suspects in the Salisbury poisoning, appeared on RT on Thursday. Both men on Thursday denied that they are GRU agents or that they were in possession of the Soviet-made Novichok nerve agent.
    IPhone Xs and iPhone Xs Max available to pre-order from today

    IPhone Xs and iPhone Xs Max available to pre-order from today

    This week Apple announced the latest incarnations of its iPhone: the iPhone XS , the iPhone XS Max, and the iPhone XR . However Apple's third new iPhone , the XR, isn't available for preorders yet.
    Trump Accuses Democrats of Altering Statistics on Hurricane Deaths in Puerto Rico

    Trump Accuses Democrats of Altering Statistics on Hurricane Deaths in Puerto Rico

    Chris Stewart said. "Then, a long time later, they started to report really large numbers, like 3000", Trump wrote on Twitter . Brock Long, the head of the US Federal Emergency Management Agency (FEMA), warned that Florence could "kill a lot of people".
  • Storm Helene downgraded, but forecasters warn coastal residents to be wary

    Storm Helene downgraded, but forecasters warn coastal residents to be wary

    Met Éireann have predicted heavy rain this afternoon and tonight in counties Donegal, West Galway, North Leitrim, Mayo and Sligo. High gusts in the 50s or low 60s mph area also possible over high ground in northern England during the early hours of Tuesday.
    Liverpool - Premier League - 15 September 2018

    Liverpool - Premier League - 15 September 2018

    And that would be a game changer for them. "I hope I have them all fit, and I don't have to make a hard decision". Wijnaldum told The Telegraph: " I met [Mauricio] Pochettino when I left Newcastle.
    Paul Manafort expected to plea to new charges filed by special counsel

    Paul Manafort expected to plea to new charges filed by special counsel

    He was convicted earlier this summer on eight out of 18 counts in a bank and tax fraud trial in Virginia federal court. For months, Manafort had refused to turn on his former boss, unlike other Trump administration figures.

We are pleased to provide this opportunity to share information, experiences and observations about what's in the news.
Some of the comments may be reprinted elsewhere in the site or in the newspaper.
Thank you for taking the time to offer your thoughts.